The ZNF265 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to zranb2. This antibody recognizes Human, Mouse, and Rat antigen. The ZNF265 Antibody has been validated for the following applications: ELISA, Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
Function: Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.
Subunit Structure: Interacts with the C-terminal half of SNRNP70, the Arg/Ser-rich domain of AKAP17A as well as with U2AF1 and CLK1.
Post-translational Modifications: Isoform 2 is phosphorylated on Ser-310 upon DNA damage, probably by ATM or ATR.
Similarity: The RanBP2-type zinc fingers mediate binding to RNA. Belongs to the ZRANB2 family